The results of another randomized trial in 39 patients with Alzheimers disease suggested that supplementation with fish oil concentrate (high in omega-3 fatty acids) with or without lipoic acid (600 mg/day) for one year could delay the progression in cognitive and functional impairments assessed by the Instrumental Activities of Daily Living (IADL) scoring system compared to placebo (104)
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This ZnT1/GluN2A complex may be influenced by synaptic plasticity, and disruptions in ZnT1 expression led to significant changes in dendritic spine morphology
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Sung JH, Shin SA, Park HK, Montelaro RC, Chong YA